Practical guides, equipment selection, and insights for improving peptide synthesis.
15 resources
How temperature and coupling time influence reaction kinetics, side reactions, and crude purity in research-scale peptide synthesis. Explore model peptide results, coupling chemistries, and the role of solvent preheating.
Read moreHow temperature control affects crude purity, yield, and process consistency as peptide synthesis moves from research to pilot and commercial scale. Explore conduction, microwave, and induction heating, solvent pre-heating, and real-time temperature feedback.
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A practical CSBio selection guide for choosing the right automated peptide synthesizer for research, process development, pilot production, GMP manufacturing, and commercial scale peptide production.
Read moreRecorded live at TIDES Europe, the leading international conference for peptides, CSBio’s Hanson Chang was invited to showcase the latest solid-phase peptide synthesis technologies to improve CMC outcomes—boosting yield and control while reducing solvent use. The talk highlights practical, scalable approaches to process development and tech transfer in peptide manufacturing.
Read moreIn this resource, we provide an introduction on how process analytical tools such as refractive index, UV, and Raman have been integrated into solid phase peptide synthesis processes.
Read moreIn collaboration with Beatriz de la Torre and Fernando Albericio, we evaluated we explored the impact of thermal management on peptide quality, with results published in TKS | TeknoScienze.
Read moreIn this case study, we showcase a few publications that utilized CSBio's peptide synthesizers in developing green SPPS methods.
Read moreIn this mini-course, we provide a series of 12 short videos that covers different SPPS activation chemistries, resin types and applications, the units in SPPS, an example of how to make a peptide with SPPS, how to prepare reagents, the synthesis cycle, and how to practically make a peptide in the lab.
Read moreIn this case study, we evaluate the effect of temperature on the speed of synthesis and crude purity.
Read moreIn collaboration with University of California, Davis; UCD evaluated microwave and conduction heating and presented the findings at the 28th American Peptide Symposium
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In this resource, we provide an extensive guide enabling users to apply the most widely-used synthetic strategies for SPPS, and helpful hints to avoid some of the obstacles that often lead to expensive mistakes and/or poor synthesis yield.
Read moreIn this article, we provide insight on the drivers and balance between synthesis speed, waste generation, purity, and finding that perfect synthesis protocol for peptide synthesizers.
Read moreIn this article, we've gathered the key things to know to adequately compare the most popular synthesizers on the market for users searching for a peptide synthesizer.
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In this case study, we talk about CSBio's peptide synthesizer platform and knowledge that allows companies to utilize our peptide synthesizers during the early days of drug discovery, all way through commerical scale manufacturing
Read moreUsing a CSBio research scale peptide synthesizer, we share a case study of how a 132-mer peptide can be synthesized with high purity
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CSBio is a leading peptide instrumentation manufacturing company located in Silicon Valley, California.
CSBio provides research scale peptide synthesizers, pilot scale peptide synthesizers, commercial scale peptide synthesizers, and DNA/RNA oligonucleotide synthesizers.