Robust | Reliable | Scalable


Ideal for R&D,
Process Development
or Small Scale Manufacturing

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Complete Instrument Synthesis Control

The most flexible fully automated peptide synthesizer on the market

Adjustable Scale

Reaction Vessels from 20 - 200 mL. Scaling up with the needs of the lab.

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Flexible Chemistry

9 Solvent reservoirs, allowing for HBTU/DIEA, HoBT/DIC or any other chemistry within the same synthesis.


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Introduction to the CS136X

The CS136X is a research scale peptide synthesizers that is used for R&D, process development, and small-scale manufacturing.

Found in large pharmaceutical companies and universities across the globe, our research scale synthesizers have reaction vessel sizes ranging from 20 ml to 200 ml that utilize our patented 180° inversion mixing for complete solvent and resin contact.

Designed to Your Needs

We work with customers to optimize their synthesizer configuration to match their desired use cases.

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Multiple Reaction Vessels

Simultaneously synthesize different peptides at the same time. Exponentially increase the output of your lab with up to 3 functional reaction vessels.

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Intuitive and Flexible Software

Powered by CSBio's CSPEPM™ software, users can see their peptide sequence, build their own step by step protocol (or utilize the provided proven standard protocols), synthesize with unlimited flexibility in protocols by amino acid allowing for different chemistries within the same peptide sequence, and perform capping or double/triple coupling on selective amino acids within the same.

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Temperature Control

Using jacketed reaction vessels, the CS136X can circulate chilled or heated water from 5°C to 90°C around the reaction during the entire synthesis. Creating a uniform and regulated temperature environment with no localized spikes which can cause racemization in your peptide.

CS136X Features

The CS136X is an automated research scale peptide synthesizer that can be found in university, startup and pharmaceutical labs world wide. All systems are custom, built to order, delivering the optimal system for their lab.

System Specs

  • 20 - 200mL Reaction Vessel Size
  • Twenty-Two 100mL Amino Acid Reserviors
  • One 5L, four 2L, two 1L and two 250ml solvent reservoirs


180° Inversion mixing with nitrogen bubbling for complete solvent and resin contact


Unlimited couplings, fully automated synthesis of sequences 130-mer or more with no user interaction

Custom Options

  • Additional functional reaction vessels (up to 3)
  • Heated synthesis with jacketed reaction vessels
  • Additional solvent / amino acid reserviors
  • UV monitoring
  • 21 CFR Part 11 Compliant Software

Installation Requirements

  • 120V or 220V power
  • Nitrogen @ 15 psi,Air Supply @ 60 psi, Vent
  • 40" wide x 30" height x 27" deep


One year full warranty covering parts and labor


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About Our Company

CSBio is a leading peptide and instrumentation manufacturing company located on the edge of
Silicon Valley in Menlo Park, California.

For over 25 years, CSBio has been providing high quality custom peptides, cGMP peptides and automated peptide synthesizers to the global pharmaceutical community. Our peptide products and instrumentation can be found in production laboratories and pharmaceutical companies worldwide.

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Our state of the art cGMP manufacturing facility and vertically integrated design and manufacturing engineering team provides the best in class products and services in the industry.

  • cGMP Peptides
  • Peptide APIs
  • Non-Clinical Peptides
  • Peptide Resins and Amino Acids
  • Research to Commercial Scale Peptide Synthesizers
  • Pilot and Process Scale DNA Synthesizers
  • Preparative HPLC Purification Equipment

About Us

CSBio is a leading peptide and instrumentation manufacturing company located in Silicon Valley, California.

CSBio provides nonGMP and cGMP peptides, peptide APIs, research scale peptide synthesizers, commerical scale peptide synthesizers, DNA/RNA oligonucleotide synthesizers, and preparative HPLC purification equipment.

Peptide Contact

20 Kelly Court
Menlo Park, CA 94025


Instrumentation Contact

915 Linda Vista Ave
Mountain View, CA, 94043