Multiple Reaction Vessels
Simultaneously synthesize different peptides at the same time. Exponentially increase the output of your lab with up to 3 functional reaction vessels.
Robust | Reliable | Scalable
CS136X
Ideal for R&D,
Process Development
or Small Scale Manufacturing
Complete Instrument Synthesis Control
The most flexible fully automated peptide synthesizer on the market
Adjustable Scale
Reaction Vessels from 20 - 200 mL. Scaling up with the needs of the lab.
Flexible Chemistry
9 Solvent reservoirs, allowing for HBTU/DIEA, HoBT/DIC or any other chemistry within the same synthesis.
Introduction to the CS136X
The CS136X is a research scale peptide synthesizers that is used for R&D, process development, and small-scale manufacturing.
Found in large pharmaceutical companies and universities across the globe, our research scale synthesizers have reaction vessel sizes ranging from 20 mL to 200 mL that utilize our patented 180° inversion mixing for complete solvent and resin contact.
Designed to Your Needs
We work with customers to optimize their synthesizer configuration to match their desired use cases.
Intuitive and Flexible Software
Powered by CSBio's CSPEPM™ software, the system displays the peptide sequence and offers users protocol flexibility, allowing them to build custom step-by-step protocols (or use standard ones), assign different chemistries or protocols by amino acid, and perform selective capping or double/triple coupling within the same synthesis run.
Temperature Control
Using heat exchangers and jacketed reaction vessels, the CS136X utilizes conduction heating that allows for the circulation of chilled or heated water from -20°C to 90°C to pre-heat solvents and reagents prior to delivery into the reaction vessel, as well as heat the reaction vessel during the entire synthesis. This creates a uniform and regulated temperature environment that improves crude peptide purity and speeds up synthesis.
CS136X Features
The CS136X is an automated research scale peptide synthesizer that can be found in university, startup and pharmaceutical labs worldwide. All systems are built to order with user configured system options, delivering the optimal system for their lab.
System Specs
- 20 - 200mL Reaction Vessel Size
- Twenty-Two 100mL Amino Acid Reserviors
- One 5L, four 2L, two 1L and two 250ml solvent reservoirs
Mixing
180° Inversion mixing with nitrogen bubbling for complete solvent and resin contact
Coupling
Unlimited couplings, fully automated synthesis of sequences 130-mer or more with no user interaction
Custom Options
- Additional functional reaction vessels (up to 3)
- Heated synthesis with jacketed reaction vessels
- Additional solvent / amino acid reserviors
- UV monitoring
- 21 CFR Part 11 Compliant Software
Installation Requirements
- 120V or 220V power
- Nitrogen @ 15 psi,Air Supply @ 60 psi, Vent
- 40" wide x 30" height x 27" deep
Warranty
One year full warranty covering parts and labor
Questions?
Speak to an Instrumentation team member today
Research Scale Synthesis Resources
The role of temperature in Solid Phase Peptide Synthesis (SPPS)
This case study explores the role of temperature on speed of synthesis and crude purity
Comparison of Microwave and Conduction Heating for Solid Phase Peptide Synthesis
In collaboration with University of California, Davis; UCD evaluated microwave and conduction heating and presented the findings at the 28th American Peptide Symposium
A Mini-Course on Solid Phase Peptide Synthesis
In this video series, we provide a 2 hour mini-course on the fundamentals and how to perform SPPS
Research Scale Peptide Synthesizers: Demystifying Purity, Synthesis Speed and Waste Generation
Understand what drives peptide synthesis purity, speed, and waste generation
About Our Company
CSBio is a leading peptide synthesis instrumentation company located in
Silicon Valley, California.
Since 1993, CSBio has been providing automated peptide synthesizers to the global pharmaceutical community. Our peptide synthesizers can be found in more than 30 countries worldwide across universities, research institutes, production laboratories, CDMOs, biotech companies, and multi-national pharmaceutical companies.
Our instrumentation design and manufacturing team provides the best in class products and services in the industry.
- Research Scale Peptide Synthesizers
- Pilot Scale Peptide Synthesizers
- Commerical Scale Peptide Synthesizers
- Pilot and Process Scale DNA Synthesizers
- Custom Build to Order Synthesizers
About Us
CSBio is a leading peptide instrumentation manufacturing company located in Silicon Valley, California.
CSBio provides research scale peptide synthesizers, pilot scale peptide synthesizers, commerical scale peptide synthesizers, and DNA/RNA oligonucleotide synthesizers.