CS336X

cs336x

Variable and Upgradable Single-Channel Solid Phase Peptide Synthesizer

The CS336X is a single-channel solid phase peptide synthesizer that can also be upgraded to utilize three reactors for multiple syntheses. It can synthesize peptides of varying lengths using preset scales and chemistries.

Like all of our synthesizers, the 336X can use either Fmoc or tBoc chemistries as the machine has been designed to handle 100% TFA. Selection of scale ranges from 0.05mmol to 0.50mmol and the machine can be shipped to utilize any preset chemistry that the end user requires.


Here are some of the other features of the CS336X:

  1. Extremely flexible software. The synthesizer will be installed with several preset programs for the user’s convenience. Additionally, the user can change existing programs or write new programs to allow complete control over every step in a synthesis. Solvent delivery, mixing times, multiple coupling/deprotection cycles and solvent volumes are among the many features that can easily be changed with the software. Our engineer can easily train chemist(s) to operate the machine (including software program) during installation.
  2. The user can purchase pre-filled amino acid cartridges from C S Bio or use their own amino acids in empty cartridges that are supplied with the machine. This is very advantageous when using very expensive or unusual amino acids.
  3. The CS336X is a very versatile peptide synthesizer. It can be purchased with one, two or three fully functional reaction vessels for simultaneous synthesis of three completely different peptide sequences. The system can be purchased with one functional reaction vessel and upgraded to utilize two or three reaction vessels at anytime. This can either be done at our facility or in the field.
  4. The synthesizer is built with a modular design. Should you have any problem with one of the components, a new component will be shipped to your facility overnight. This helps eliminate service technician visits and helps to reduce costly downtime. Should an on-site visit be required, we will repair the synthesizer at your facility.
  5. The synthesizer is built with a modular design. Should you have any problem with one of the components, a new component will be shipped to your facility overnight. This helps eliminate service technician visits and helps to reduce costly downtime. Should an on-site visit be required, we will repair the synthesizer at your facility.
  6. We have installed systems in many countries including the USA, Canada, China, India, Germany, Sweden, The Netherlands, Switzerland, Saudi Arabia, and the UK. All of our synthesizers are installed by a C S Bio engineer (regardless of world location) and you will receive 2 days of on-site training at your facility. Part of the training includes making a peptide on the synthesizer and performing a resin cleavage to assure that you are comfortable and confident with the equipment.

SPECIFICATIONS for CS336X

Reaction vessel – 1, 2, or 3 reaction vessels operating simultaneously, synthesizing 1 to 3 peptides

Reaction vessel size – 10 ml, 20 ml, 50 ml

Synthesis scale – 0.01 mmol to 0.5 mmol

Metering vessel size – 1 x 15 & 1 x 10 ml

Transfer vessel size – 1 x 50 ml

Amino acid reservoir – 10 ml cartridges using powdered amino acids, for justin-time dissolution and activation

Unattended couplings – 36

Solvent bottles – 7

Solvent bottle size – 1 x 2 L, 4 x 1 L, 2 x 0.5 L

Waste carboy – 1 x 10 L

Solvent transfer – Inert Nitrogen

Reaction vessel agitation – 180º inversion and nitrogen bubbling

Chemistry – t-Boc, Fmoc, or both

Activation – HBTU/DIEA or HOBt/DIC or any other

Product Contact – FDA compliant glass, Teflon and polyethylene

Cabinet Construction – All chemically inert, self-contained, polypropylene

Dimensions:
W x D x H (including the wheel)
34″ x 24″ x 42″ / 86 cm x 61 cm x 107 cm
Weight 110 lbs / 50 kgs

Optional
Additional solvent input lines and bottles
Onboard cleavage system
Feedback in-line UV monitoring

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