Oxyntomodulin, human, mouse, rat
Synonym: Glucagon-37, human, mouse, rat
Product Code: CS9100

His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-Lys-Arg-Asn-Arg-Asn-Asn-Ile-Ala

C₁₉₂H₂₉₅N₆₁O₆₀S
MW: 4449.85
CAS: [159002-68-3]
Longterm storage temperature: -20 C

Oxyntomodulin potently inhibits gastric acid secretion and pancreatic enzyme secretion when infused iv. Moreover, it was shown that intracerebroventricularly and into the hypothalamic paraventricular nucleus injected oxyntomodulin inhibits food intake in fasted and nonfasted animals potently and in a sustained manner.

Literature:
C.L.Dakin et al., Endocrinology, 142, 4244 (2001)
N.E.White et al., Diabetes Obes. Metab., 10, 167 (2008)