MOG (35-55), mouse, rat
Synonym: Myelin Oligodendrocyte Glycoprotein (35-55), mouse, rat
Product Code: CS0681

Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys

C₁₁₈H₁₇₇N₃₅O₂₉S_S
MW: 2581.96
CAS: [149635-73-4]
Longterm storage temperature: -20 C

MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical, histopathologic, and immunologic similarities with multiple sclerosis (MS), this MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS.

Literature:
M.Ichikawa et al., J. Immunol., 157, 919 (1996)
J.Liu et al., Nat. Med., 4, 78 (1998)