(Met(O)27)-Glucagon (1-29), human, rat, porcine
Product Code: CS9202

H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met(O)-Asn-Thr-OH
Trifluoroacetate salt

C₁₅₃H₂₂₅N₄₃O₅₀S
MW:3498.80
CAS: [75217-63-9]
Longterm storage temperature: -20 C

This glucagon derivative shows the same maximal glucose mobilizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor.

Literature:
W.J.Nooijen and H.J.Kempen, Horm. Metab. Res., 11, 459 (1979)