Endothelin-1, human
Product Code: CS1698

Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp
(Disulfide bonds 1-15, 3-11)

C₁₀₉H₁₅₉N₂₅O₃₂S₅
MW: 2491.94
CAS: [117399-94-7]
Longterm storage temperature: -20 C

This 21-amino acid peptide from vascular endothelial cells of different mammalian species is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1.

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