(Des-octanoyl)-Ghrelin, mouse, rat
Product Code: CS9096

Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

C₁₃₉H₂₃₁N₄₅O₄₁
MW: 3188.63
CAS: [307950-60-3]
Longterm storage temperature: -20 C

In contrast to the octanoylated peptide, the non-acylated ghrelin does not activate growth hormone secretagogue receptor-expressing cells. The peptide decreases food intake and gastroduodenal motility in conscious rats, probably by crossing the blood-brain barrier and activating the brain receptor directly.

Literature:
H.Hosoda et al., Biochem. Biophys. Res. Commun., 279, 909 (2000)
K.Toshinai et al., Endocrinology, 147, 2306 (2006)