Calcitonin, human
Product Code: CS0898

Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2
(Disulfide bond 1-7)

C₁₅₁H₂₂₆N₄₀O₆₅S₃
MW: 3417.81
CAS: [21215-62-3]
Longterm storage temperature: -20 C

Inhibits gastrin and gastric acid secretion. Human calcitonin stimulates cyclic nucleotide accumulation in human kidney cortex and medulla. Calcitonin maybe involved in osteoporosis and in Pagets disease.

Literature:
P.Sieber et al., Helv. Chim. Acta, 51, 2057 (1968)
K.H.Antonin et al., Clin. Sci., 83, 627 (1992)
Raddino, R. et al. J. Cardiovas. Pharmacol. 29, 463 (1997)
Rotella, C. et al. Eur. J. Pharmacol. 107, 347 (1985)
Moriarty, et al. Biochem Biophys Res. Commun. 245, 344 (1998)
Chen, W. et al. Mol. Pharmacol. 52, 1164 (1997)