β-Amyloid (25-35)
Product Code: CS0118

Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met

C₄₅H₈₁N₁₃O₁₄S
MW: 1060.28
CAS: [131602-53-4]
Longterm storage temperature: -20 C

The biologically active domain of the amyloid β-protein for neurotrophic and neurotoxic effects is located in the β (25-35) sequence, which is homologous to a region in peptides of the tachykinin family. Aß (25-35) is the main factor responsible for Aß neurotoxic effects.

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C.J.Pike et al., J. Neurochem., 64, 253 (1995) Carvalho, K. et al. Braz. J. Med. Biol. Res. 3, 1153 (1997)