β-Amyloid (10-20)
Product Code: CS9073
Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
C71H99N17O16
MW: 1446.64
CAS: [152286-31-2]
Longterm storage temperature: -20 C
The amyloid precursor protein (APP) is cleaved within the amyloid β-protein region by a putative APP secretase to release its extracellular portion. Gelatinase A, the matrix metalloproteinase MMP-2, possesses such APP secretase-like activity, effectively hydrolyzing also the synthetic amyloid β-protein fragment (10-20) at the normal processing site, the Lys16-Leu17 bond (Km approx. 0.13 mM).
Literature:
K.Miyazaki et al., Nature, 362, 839 (1993)
| Unit | Price per Unit |
| 5 mg |
$160
|
| 10 mg |
$280
|
|