C S Bio Co.

β-Amyloid (1-43)
Product Code: CS9079

H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-OH

C₂₀₇H₃₁₈N₅₆O₆₂S
MW:4615.21
CAS: [134500-80-4]
Longterm storage temperature: -20 C

The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.

Literature:
D.Goldgaber et al., Science, 235, 877 (1987)
B.A.Yankner et al., Science, 250, 279 (1990)
C.J.Pike et al., J. Neurosci., 13, 1676 (1993)
L.Gregori et al., J. Biol. Chem., 270, 19702 (1995)