Amylin, mouse, rat
Synonym: IAPP, mouse, rat; Islet amyloid polypeptide, mouse, rat
Product Code: CS3265

H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
di sulfide bond

C₁₆₇H₂₇₂N₅₂O₅₃S₂
MW:3920.45
CAS: [124447-81-0]
Longterm storage temperature: -20 C

Rat amylin (rIAPP) lacks the fibril-forming capacity of human amylin (hIAPP). As a consequence, toxic effects have been reported for the human but not for the rat peptide. The sequence of H-9475 is identical to mouse IAPP.

Literature:
J.D.Leffert et al., Proc. Natl. Acad. Sci. USA, 86, 3127 (1989)
H.A.Golpon et al., Peptides, 24, 1157 (2003)
J.Green et al., J. Mol. Biol., 326, 1147 (2003)